In clinical studies, the incidence of hypothyroidism during Sermorelin therapy was %. In the largest clinical study, 8 of 110 enrolled patients were on thyroid replacement therapy prior to Sermorelin therapy and an additional 5 after initiating therapy. Untreated hypothyroidism can jeopardize the response to Sermorelin . Therefore, thyroid hormone determinations should be performed before the initiation and throughout the duration of Sermorelin therapy. Thyroid hormone replacement therapy should be initiated when indicated.
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