OMICS International is the proud host of the 4 th Global Summit on Toxicology which took place in Philadelphia, USA during August 24-26, 2015 with the theme, “Exploring the Tailored Strategies and Lucid Technologies in Toxicology and Pharmacology”. The Editorial Board Members of OMICS Group Journals and the Organizing Committee Members of the conference have extended their unsparing support and active participation towards Toxicology 2015. The participants included eminent speakers, scientists, industrialists, delegates, researchers and students who thoroughly relished the conference.
A leading research journal in the field of pharmacology, JPET provides broad coverage of all aspects of the interactions of chemicals with biological systems, including autonomic, behavioral, cardiovascular, cellular, clinical, developmental, gastrointestinal, immuno-, neuro-, pulmonary, and renal pharmacology, as well as analgesics, drug abuse, metabolism and disposition, chemotherapy, and toxicology. The Special Libraries Association has included JPET in its DBIO 100, the "100 most influential journals of biology and medicine over the 100 years of the association."
The response is equal to the effect, or ( E ), and depends on both the drug binding and the drug-bound receptor then producing a response; thus, potency depends on both affinity and efficacy. The agonist, the ligand, drug or hormone that binds to the receptor and initiates the response is usually abbreviated A or D . Below a certain concentration of agonist ( [A] ), E is too low to measure but at higher concentrations it becomes appreciable and rises with increasing agonist concentration [A] until at sufficiently high concentrations it can no longer be increased by raising [A] and asymptotes to a maximum E max .