Use industry standard molecular mechanics forcefields such as AMBER 94/99, CHARMM 27, MMFF94 (s), OPLS -AA and Engh-Huber that run on multiple CPU threads. Amber12:EHT uses Amber12 parameters for macromolecules and Extended H ü ckel Theory parameterization for small molecules that takes electronic effects into account. Calculate partial charges including AM1-BCC charges [Jakalian 2002]. Choose from gas phase, distance dependent dielectric, reaction field and GB/VI Generalized Born [Labute 2008] implicit solvent electrostatics. Use Rigid-Body energy minimization for fusion protein construction.
Hypercube is pleased to announce a new release of its Mac Product. It is Available free to existing customers of the 2006 Product. The new release is HyperChem for Mac 2007. It is a rich product that was built from scratch for OSX and offers most of the features of our long-standing Windows product including some from the new Release 8 of the Windows product - as Undo, Rendering of POINT, LINE, and PLANE, and additions to the model builder.
The current product is available for all Macs - either those based on the PowerPC processor that Apple has traditionally used or the new Intel Macs. These include the Mac mini, iMac, iBook, PowerBook, and Power Mac.