Thinning Skin and Hydrocortisone Cream? What are the risks associated with cortisone creams? The primary risk, and what most seem to be concerned about, is thinning of the skin. While that is indeed a risk of using cortisone creams, it is important to stress that this is uncommon, and a risk that develops primarily from long-term, chronic (and excessive) use of cortisone creams. Despite this fact, many people fear thinning of skin is a risk even with responsible use of such treatments, or that it will happen immediately, and that is not the case. [2,3,4]
Dose and administration: Apply hydrocortisone cream to the affected area as a thin film 2 to 4 times daily depending on the severity of the condition. It is not likely other drugs you take orally or inject will have an effect on topically applied hydrocortisone. But many drugs can interact with each other. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, hydrocortisone should be used only when prescribed. Infants born to mothers who have been using this medication for an extended period of time may have hormone problems. Tell your doctor if you notice symptoms such as persistent nausea/vomiting, severe diarrhea, or weakness in your newborn. This medication passes into breast milk. However, this drug is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.